Update Panel slowness problem

Here are few tricks which can boost the working of Update Panel as they eliminate/minimize the huge data transfer in asynchronous calls.
1.       Set the UpdateMode property conditional for each Update-Panel.
      Ex.- UpdateMode="Conditional" ;
2.       Use multiple Update Panel  for each logical section of a webpage so that only a small portion of page which  
          requires to be independently updated/refreshed can communicate/transfer.
3.       Focus on ViewState usage (in terms of data) and minimize it.
4.       Set IsPostBack = true, so that page life-cycle on server-side can be optimized.
5.       Use PageRequestManager. It manages the Update Panel's asynchronous callbacks.